A correspondence describing DoCM has been published in Nature Methods: DoCM: a database of curated mutations in cancer. Nature Methods (2016) doi:10.1038/nmeth.4000.
Major website update. A new importing system was implemented to facilitate batch imports. This streamlines the import process and is documented in the batch submission help page. The database was reorganized in to batches and reprocessed through the new automated importer.
Database update. Automatic importer implemented to automatically import relevant variants from CIViC, a database of clinical interpretations of variants in cancer.
API versioning system implemented, allowing past snapshots of the database to be queried.
DoCM cited by Wagner, A. H. et al. DGIdb 2.0: mining clinically relevant drug-gene interactions. Nucleic Acids Res 44, D1036-1044, doi:10.1093/nar/gkv1165 (2016).. Drug-gene interactions from DoCM are now aggregated along with other sources in DGIdb'.
Database update. Integrated variants from LE MacConail et al. 2014. 360 new variants from 63 genes representing 35 different cancer subtypes.
DoCM cited by Krogan, N. J., Lippman, S., Agard, D. A., Ashworth, A. & Ideker, T. The cancer cell map initiative: defining the hallmark networks of cancer. Mol Cell 58, 690-698, doi:10.1016/j.molcel.2015.05.008 (2015)..
DoCM cited by McGranahan, N. et al. Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. Sci Transl Med 7, 283ra254, doi:10.1126/scitranslmed.aaa1408 (2015)..
DoCM presented at AGBT in San Marco Island, Fl.
DoCM presented at the AACR Translation of the Cancer Genome meeting in San Fransisco.
Database update. Variants and metadata added from Dienstmann et al. 2014.
DoCM Beta test launch. Please submit feedback to Ben Ainscough.
DoCM by The McDonnell Genome Institute at Washington University School of Medicine is licensed under a Creative Commons Attribution 4.0 International License. Questions? Comments? Concerns? You can contact us here.